Health Care Workers and Patients as Trojan Horses: a COVID19 ward outbreak

Siderophores as “Trojan Horses”: tackling multidrug resistance?

Microbial drug resistance is partly due to hindered diffusion through the membrane of microbial cells and active transport mechanisms. An approach to counter such resistance uses the bacterial iron transport system. Extracellular free iron is scarce in vertebrates, yet essential for microbial growth (Anderson et al., 2012). A mechanism displayed by microbial pathogens to cope with iron scarcity...

The Death awareness and Spiritual Experience of Health Care Workers during Coronavirus Outbreak

Introduction: The present study aims to identify the death awareness and spiritual experience of the health care workers in Iran. Methods: Eleven health care workers involved with Coronavirus patients were selected through purposeful sampling and had in-depth semi-structured interviews. Conventional content analysis was utilized to analyze the data. Results: The conventional content analysis...

False friends: Phagocytes as Trojan horses in microbial brain infections

Humans are constantly exposed to pathogenic microbes. The first line of cellular host defense is composed of “professional” phagocytes, cells that efficiently recognize pathogens, internalize them, and then marshal an array of antimicrobial mechanisms to destroy them. Nevertheless, successful pathogens evade or survive such attack. A particularly subversive strategy is to manipulate normal phag...

Silicon particles as trojan horses for potential cancer therapy

BACKGROUND Porous silicon particles (PSiPs) have been used extensively as drug delivery systems, loaded with chemical species for disease treatment. It is well known from silicon producers that silicon is characterized by a low reduction potential, which in the case of PSiPs promotes explosive oxidation reactions with energy yields exceeding that of trinitrotoluene (TNT). The functionalization ...

Compiler Implementation Verification and Trojan Horses